Drug groups

List of drug groups according to their anatomotherapeutic-chemical classification:

ATC drug classification

International system of classification of medicinal products

The ATC drug classification is used in many countries to label and study medicinal products.

Each code contains 7 characters denoting 5 levels of diversification:

The first level, the first sign, is a Latin orthographic letter indicating the anatomical area, the diseased organ, which is treated with the given medicinal products - this is the main anatomical group.

The second level, second and third characters, represent Arabic numerals - the main therapeutic group.

The third level, the fourth sign, is also a Latin spelling letter - the therapeutic subgroup.

The fourth level, the fifth character, indicates the chemical group of the medicinal product.

The fifth level, the sixth and seventh characters, are again Arabic numerals and indicate the name of the active ingredient of the medicinal product or medicinal combination.

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Toxicological risk during pregnancy

We use the commonly known FDA classification


Toxicological risk during lactation

Toxicological lactation category I - the drug and/or its metabolites are either not eliminated through breast milk or are not toxic to the newborn and cannot lead to the development of absolutely any toxic reactions and adverse consequences for his health in the near and long term. Breast-feeding does not need to be discontinued while taking a given drug that falls into this toxicological lactation category.

Toxicological lactation category II - the drug and its metabolites are also eliminated through breast milk, but the plasma:milk ratio is very low and/or the excreted amounts cannot generate toxic reactions in the newborn due to various reasons, including degradation of the drug in the acid pool of the stomach of the newborn. Breastfeeding does not need to be discontinued while taking this medicine.

Toxicological lactation category III - the drug and/or its metabolites generate in breast milk equal to plasma concentrations or higher, and therefore the possible development of toxic reactions in the newborn can be expected. Breastfeeding should be discontinued for the period corresponding to the complete elimination of the drug or its metabolites from the mother's plasma.

Toxicological lactation category IV - the drug and/or its metabolites generate a plasma:milk ratio of 1:1 or higher and/or have a highly toxic profile for both the mother and the newborn, therefore their administration is incompatible with breastfeeding and it should to stop completely, and not just for the period of taking the drug, or to look for a less toxic therapeutic alternative.